the aim of this investigation was to design and develop nanoemulsions (nes) as novel ophthalmic delivery systems for brinzolamide (bzd). phase behavior of quaternary systems composed of triacetin and capryoltm 90 (selected oils, screened through the solubility studies), various surfactants (namely, cremophor rh 40, brij 35, labrasol and tyloxapol), transcutol p (as co-surfactant) and water a...

the aim of this study is to formulate a novel ophthalmic nanosuspension (ons), an alternative carrier system to traditional colloidal carriers for controlled release (cr) of acyclovir (acv). in the present study, ons is employed to avoid some of major disadvantages of colloidal carriers systems such as instability in cul de sac and short half life by increasing efficiency of drug encapsulation ...

Ophthalmic In-situ gels are viscous polymer‐based liquids that exhibit sol‐to‐gel phase transition on the ocular surface due to change in a specific physicochemical parameter like ionic strength, pH or temperature Gel dosage forms are successfully used as drug delivery systems considering their ability to prolong the drug release. To prolong the precorneal resident time and improve ocular bioav...